My wife's great grandmother was reported to be Cherokee. Her maiden name was Nancy Pittman and she married Eli Lawrence. Nancy's mother was named Comfort Hatfield and she married Daniel Pittman. With a first name like Comfort the Indian connection certainly seemed possible. Comfort was born in Kentucky about 1810.
Another Lawrence family researcher recently found a Guion Miller application that was submitted by Nancy's nephew in 1907. The application was denied because he didn't have any written proof but in it he said Nancy's grandmother was named Annie Ross and she was one quarter Cherokee.